Description

4-Chloro-2-Hydroxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a chloro substituent and a hydroxyl group, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for APIs targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Research & Development: A fundamental building block for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	4-Chloro-2-Hydroxypyridine
CAS No.	40673-25-4
Molecular Formula	C5H4ClNO
Molecular Weight	129.54 g/mol
Synonyms	2-Hydroxy-4-chloropyridine; 4-Chloro-2-pyridinol; 4-Chloro-2(1H)-pyridinone; 4-Chloro-1H-pyridin-2-one; 4-Chloro-2-oxo-1,2-dihydropyridine; 4-Chloro-2-pyridone; 2-Pyridinol, 4-chloro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Hydroxypyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.