Description

n-[2-[3,5-Bis(trimethylsiloxy)phenyl]-2-(trimethylsiloxy)ethyl]-n-isopropyl-2,2,2-trifluoroacetamide is a specialized organosilicon compound featuring a trifluoroacetamide group, designed for advanced synthetic and material science applications. Its unique structure, incorporating multiple trimethylsiloxy (TMS) protecting groups, makes it a valuable intermediate for constructing complex molecules with precise control over reactivity and solubility. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those requiring silicon-containing or fluorinated motifs for enhanced metabolic stability and bioavailability.
• Advanced Material Synthesis: Used in the development of specialty silicones, silicone-modified polymers, and other high-performance materials where the TMS groups act as protective or modifying agents.
• Agrochemical Research: Functions as a precursor in creating novel active ingredients for crop protection, leveraging the trifluoroacetamide moiety for specific biological activity.
• Organic Synthesis Reagent: Acts as a versatile reagent in multi-step synthetic routes, where its siloxy groups provide temporary protection for hydroxyl functionalities under various reaction conditions.
• Surface Modification Agent: Employed in the functionalization of surfaces (e.g., silica, glass) to impart specific hydrophobic or chemical properties.

Basic Information

Product Name	n-[2-[3,5-Bis(trimethylsiloxy)phenyl]-2-(trimethylsiloxy)ethyl]-n-isopropyl-2,2,2-trifluoroacetamide
CAS No.	40629-68-3
Molecular Formula	C21H38F3NO5Si3
Molecular Weight	525.78 g/mol
Synonyms	N-Isopropyl-N-[2-[3,5-bis(trimethylsiloxy)phenyl]-2-(trimethylsiloxy)ethyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[2-[3,5-bis[(trimethylsilyl)oxy]phenyl]-2-[(trimethylsilyl)oxy]ethyl]-N-(1-methylethyl)acetamide; N-[2-[3,5-Bis(trimethylsiloxy)phenyl]-2-(trimethylsiloxy)ethyl]-N-isopropyltrifluoroacetamide; Trifluoroacetamide siloxy derivative; TMS-protected trifluoroacetamide intermediate
EINECS	Contact for details

Quality Control

Our n-[2-[3,5-Bis(trimethylsiloxy)phenyl]-2-(trimethylsiloxy)ethyl]-n-isopropyl-2,2,2-trifluoroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.