Description

2-Acetoacetylpyridine is a versatile pyridine derivative and a key organic intermediate characterized by its reactive β-diketone functionality. This compound is essential for the synthesis of complex heterocyclic structures, offering significant value in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its heterocyclic core contributes to biological activity.
• Ligand and Chelating Agent Precursor: Serves as a starting material for creating specialized ligands used in catalysis and metal complexation.
• Heterocyclic Chemistry Research: A fundamental reagent in academic and industrial R&D for constructing complex nitrogen-containing ring systems like pyrazoles and isoxazoles.
• Material Science: Investigated for use in the synthesis of organic electronic materials and functional polymers.
• Chemical Synthesis: Employed in various organic transformations, including condensation and cyclization reactions, to create specialty fine chemicals.

Basic Information

Product Name	2-Acetoacetylpyridine
CAS No.	40614-52-6
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	1-(2-Pyridinyl)-1,3-butanedione; 2-Acetoacetyl pyridine; 2-Pyridyl acetoacetate; 1,3-Butanedione, 1-(2-pyridinyl)-; 2-Acetylacetylpyridine; 2-(2-Oxobutanoyl)pyridine; 2-Pyridylacetylacetone; 2-Acetoacetylpyridine
EINECS	Contact for details

Quality Control

Our 2-Acetoacetylpyridine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.