Description

Diethyl-(2-Oxo-4-Phenylbutyl)Phosphonate, 98 % is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective construction of complex α,β-unsaturated carbonyl systems. This makes it an essential material for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to create novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of biologically active molecules, including potential drug candidates with anti-inflammatory, antiviral, or anticancer properties.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific alkene geometries.
• Fine Chemical Manufacturing: Employed in the construction of complex fragrances, flavors, and specialty chemicals where precise control over double bond formation is crucial.
• Academic & Industrial R&D: A fundamental reagent in methodology development and the synthesis of novel organic compounds for material science and chemical biology.
• Synthesis of α,β-unsaturated carbonyl compounds: Specifically used to generate chalcones, stilbenes, and other important scaffolds with high (E)-selectivity.

Basic Information

Product Name	Diethyl-(2-Oxo-4-Phenylbutyl)Phosphonate, 98 %
CAS No.	40601-45-4
Molecular Formula	C₁₄H₂₁O₄P
Molecular Weight	284.29 g/mol
Synonyms	Diethyl (2-oxo-4-phenylbutyl)phosphonate; (2-Oxo-4-phenylbutyl)phosphonic acid diethyl ester; Diethyl (4-phenyl-2-oxobutyl)phosphonate; 4-Phenyl-2-oxobutylphosphonic acid diethyl ester; Diethyl 2-oxo-4-phenylbutylphosphonate; HWE Reagent (phenyl variant); Phosphonoacetic acid, (2-oxo-4-phenylbutyl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl-(2-Oxo-4-Phenylbutyl)Phosphonate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98% minimum purity and consistent performance as a synthesis reagent. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The product is stable under recommended storage conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.