Description

2-Bromo-6-Methoxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic reactivity of the bromine atom, which enables efficient cross-coupling reactions for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and functional polymers.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-heteroatom bonds.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting.
• Ligand Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Item	Detail
Product Name	2-Bromo-6-Methoxypyridine
CAS No.	40473-07-2
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	6-Methoxy-2-bromopyridine; 2-Bromo-6-methoxypyridine; 2-Bromo-6-pyridinol methyl ether; 6-Methoxy-2-bromopyridine; 2-Bromo-6-methoxypyridine; 2-Brom-6-methoxypyridin; 40473-07-2
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS and NMR for identity confirmation, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.