Description

5-Methylnicotinic Acid Hydrochloride is a high-purity organic salt derivative of nicotinic acid, serving as a critical pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in providing a functionalized pyridine core essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides that require specific pyridine-based structures for efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed coupling reactions and coordination chemistry.
• Fine Chemical Production: Employed in the manufacture of complex dyes, pigments, and other performance chemicals where the methylnicotinate moiety is required.
• Biochemical Research: Utilized as a standard or reagent in metabolic pathway studies and enzymatic assays related to niacin (vitamin B3) chemistry.
• Material Science: Acts as a monomer or additive in the synthesis of advanced polymers and functional materials.

Basic Information

Product Name	5-Methylnicotinic Acid Hydrochloride
CAS No.	40473-04-9
Molecular Formula	C7H8ClNO2
Molecular Weight	173.60 g/mol
Synonyms	5-Methylnicotinic Acid HCl; 3-Carboxy-5-methylpyridine Hydrochloride; 5-Methylpyridine-3-carboxylic Acid Hydrochloride; 5-Methyl-3-pyridinecarboxylic Acid Hydrochloride; Nicotinic Acid, 5-Methyl-, Hydrochloride; 5-Picolinic Acid, 3-Methyl-, Hydrochloride (obsolete); 40473-04-9 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 5-Methylnicotinic Acid Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all test results against established specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.