Description

2-Bromo-5-Chloropyridine is a versatile and high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides, where the halogenated pyridine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting compounds.
• Custom Chemical Synthesis: A fundamental building block for contract research organizations (CROs) and custom synthesis houses developing proprietary compounds for clients.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2-Bromo-5-Chloropyridine
CAS No.	40473-01-6
Molecular Formula	C5H3BrClN
Molecular Weight	192.44 g/mol
Synonyms	5-Chloro-2-bromopyridine; 2-Bromo-5-chloropyridine; 5-Chloro-2-pyridyl bromide; 2-Bromo-5-chloro-pyridine; 2-Pyridyl bromide, 5-chloro-; 40473-01-6; Bromochloropyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Chloropyridine is produced and tested under a strict quality management system to ensure high purity and batch-to-batch consistency. Our standard grade typically meets a purity specification of ≥98% (by HPLC), with comprehensive testing for identity, assay, and related substances. A detailed Certificate of Analysis (COA) is provided with each shipment, and we can support development projects with analytical method validation data upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.