Description

5-(Pyridin-4-Yl)Thiazol-2-Amine is a high-purity heterocyclic organic compound featuring a fused pyridine-thiazole structure, serving as a critical building block in advanced chemical synthesis. This compound matters for its role as a versatile pharmacophore and key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating new molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antimicrobial agent discovery.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research: Serves as a fundamental building block in organic and medicinal chemistry for constructing complex heterocyclic libraries.
• Material Science: Potential precursor for the synthesis of organic ligands in coordination chemistry and functional materials.
• Bioconjugation & Probe Development: The amine functional group allows for derivatization, making it useful for creating fluorescent probes or biochemical tags.

Basic Information

Product Name	5-(Pyridin-4-Yl)Thiazol-2-Amine
CAS No.	40353-55-7
Molecular Formula	C8H7N3S
Molecular Weight	177.23 g/mol
Synonyms	4-(2-Aminothiazol-5-yl)pyridine; 2-Amino-5-(4-pyridinyl)thiazole; 5-(4-Pyridinyl)-2-thiazolamine; 5-(4-Pyridyl)thiazol-2-amine; 2-Thiazolamine, 5-(4-pyridinyl)-; 5-Pyridin-4-yl-thiazol-2-ylamine; 5-(Pyridin-4-yl)-1,3-thiazol-2-amine
EINECS	Contact for details

Quality Control

Our 5-(Pyridin-4-Yl)Thiazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.