Description

2-Chloro-4-Ethylpyridine is a versatile halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and high-value agrochemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production for materials science. Its specific substitution pattern offers precise reactivity for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, including charge-transport layers and photoactive compounds.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry optimization in laboratory-scale and pilot-scale operations.
• Custom Synthesis: Provides a functionalized handle for contract research and manufacturing organizations (CROs/CMOs) to build custom, complex molecules for clients.

Basic Information

Product Name	2-Chloro-4-Ethylpyridine
CAS No.	40325-11-9
Molecular Formula	C7H8ClN
Molecular Weight	141.60 g/mol
Synonyms	4-Ethyl-2-chloropyridine; 2-Chloro-4-ethylpyridine; 4-Ethyl-2-pyridinyl chloride; Pyridine, 2-chloro-4-ethyl-; 2-Chloro-4-ethyl-pyridine; 2-Chloro-4-ethylpyridine (major); 40325-11-9 (CAS RN)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Ethylpyridine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.12 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.