Description

2-(2-Chloro-3-Fluoropyridin-4-Yl)Propan-2-Ol is a high-purity fluorinated pyridine derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique halogenated structure, which serves as a versatile building block for constructing complex molecules with targeted biological or material properties. This compound is essential for R&D and production within the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and manufacturing of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for enhanced bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and functional polymers due to its fluorinated aromatic system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(2-Chloro-3-Fluoropyridin-4-Yl)Propan-2-Ol
CAS No.	40273-52-7
Molecular Formula	C8H9ClFNO
Molecular Weight	189.61 g/mol
Synonyms	2-(2-Chloro-3-fluoropyridin-4-yl)propan-2-ol; 2-(2-Chloro-3-fluoro-4-pyridinyl)-2-propanol; 4-(2-Hydroxy-2-propyl)-2-chloro-3-fluoropyridine; 2-Chloro-3-fluoro-4-(2-hydroxypropan-2-yl)pyridine; 2-Propanol, 2-(2-chloro-3-fluoro-4-pyridinyl)-; 40273-52-7; 2-(2-Chloro-3-fluoropyridin-4-yl)-2-propanol
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-3-Fluoropyridin-4-Yl)Propan-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.