Description

2-Bromo-3-Fluoropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a valuable precursor for introducing functional complexity into target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized for synthesizing fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Scale-up: A fundamental starting material for contract research organizations (CROs) and CDMOs performing custom synthesis projects.

Basic Information

Product Name	2-Bromo-3-Fluoropyridine
CAS No.	40273-45-8
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	3-Fluoro-2-bromopyridine; 2-Bromo-3-fluoropyridine; 3-Fluoropyridine, 2-bromo-; Pyridine, 2-bromo-3-fluoro-; 2-Bromo-3-fluoro-pyridine; 40273-45-8; 3-Fluoro-2-bromo-pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and residual solvent analysis, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed and stored upright in a secondary containment area.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.