Description

2-Iodo-3-Hydroxypyridine is a halogenated pyridine derivative serving as a versatile and high-value synthetic building block in advanced organic chemistry. Its unique structure, combining an iodine substituent with a hydroxyl group on the pyridine ring, makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences, agrochemical, and material science sectors seeking to introduce specific functional groups or create novel heterocyclic systems. We supply this material with a focus on consistent purity and reliable global supply chains to support your critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that require halogenated pyridine motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis houses and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Iodo-3-Hydroxypyridine
CAS No.	40263-57-8
Molecular Formula	C5H4INO
Molecular Weight	220.99 g/mol
Synonyms	3-Hydroxy-2-iodopyridine; 2-Iodo-3-pyridinol; 3-Pyridinol, 2-iodo-; 2-Iodopyridin-3-ol; 3-Hydroxy-2-iodo-pyridine
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment ensures material traceability, batch-to-batch consistency, and compliance with relevant guidelines for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.