Description

Methyl 3-Chloro-4-Hydroxy-5-Nitrobenzoate is a high-purity, multi-functional benzoate ester derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a chlorinated, nitrated phenolic scaffold.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and insecticides, where its nitro and chloro groups contribute to biological activity.
• Dye and Pigment Chemistry: Serves as a starting material for the production of specialized azo dyes and organic pigments due to its reactive phenolic and ester functionalities.
• Ligand and Catalyst Development: Employed in academic and industrial research to create novel chelating ligands for metal catalysts used in cross-coupling and other organic transformations.
• Material Science Research: Investigated as a monomer or additive for the synthesis of specialty polymers with tailored properties like UV absorption or thermal stability.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in bespoke, multi-step synthetic routes for client-specific target molecules.

Basic Information

Product Name	Methyl 3-Chloro-4-Hydroxy-5-Nitrobenzoate
CAS No.	40256-81-3
Molecular Formula	C8H6ClNO5
Molecular Weight	231.59 g/mol
Synonyms	3-Chloro-4-hydroxy-5-nitrobenzoic acid methyl ester; Methyl 3-chloro-4-hydroxy-5-nitrobenzoate; Benzoic acid, 3-chloro-4-hydroxy-5-nitro-, methyl ester; 4-Hydroxy-3-chloro-5-nitrobenzoic acid methyl ester; Methyl 4-hydroxy-3-chloro-5-nitrobenzoate; 3-Chloro-4-hydroxy-5-nitro-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-4-Hydroxy-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.