Description

1(2H)-Pyridinecarbonyl Chloride, 3,6-Dihydro- (9Ci) is a highly reactive acid chloride derivative of a partially saturated pyridine ring, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the 3,6-dihydro-2H-pyridine-1-carbonyl moiety, a versatile scaffold for constructing complex nitrogen-containing heterocycles. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used to synthesize complex chelating ligands for metal catalysis and coordination chemistry.
• Material Science Research: Intermediate for producing functional polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and APIs on a commercial scale.

Basic Information

Item	Details
Product Name	1(2H)-Pyridinecarbonyl Chloride, 3,6-Dihydro- (9Ci)
CAS No.	40240-41-3
Molecular Formula	C6H6ClNO
Molecular Weight	143.57 g/mol
Synonyms	3,6-Dihydro-2H-pyridine-1-carbonyl chloride; 1,2,3,6-Tetrahydropyridine-1-carbonyl chloride; 2,3-Dihydro-1H-pyrrolizine-7-carbonyl chloride (related structure); DHP-COCl; 1-Carboxy-1,2,3,6-tetrahydropyridine chloride; 1-Chlorocarbonyl-1,2,3,6-tetrahydropyridine; Tetrahydropyridine-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1(2H)-Pyridinecarbonyl Chloride, 3,6-Dihydro- (9Ci) is manufactured and tested under strict quality management systems to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.