Description

2-Pyridinemethanamine, A-Methyl-, Dihydrochloride, (As)- is a high-purity chiral amine derivative, specifically the dihydrochloride salt of (S)-1-(pyridin-2-yl)ethan-1-amine. This compound matters as a critical chiral building block and ligand in asymmetric synthesis, offering precise stereochemical control for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of high-quality, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis: Used as a chiral ligand or catalyst component in transition metal-catalyzed reactions, such as hydrogenations and cross-couplings.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Chemical Research & Development: A valuable reagent for methodological studies in organic and medicinal chemistry focused on stereoselective synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	2-Pyridinemethanamine, A-Methyl-, Dihydrochloride, (As)-
CAS No.	40154-78-7
Molecular Formula	C8H14Cl2N2
Molecular Weight	209.11 g/mol
Synonyms	(S)-1-(Pyridin-2-yl)ethan-1-amine dihydrochloride; (S)-(-)-α-Methyl-2-pyridinemethanamine dihydrochloride; (S)-1-(2-Pyridinyl)ethylamine dihydrochloride; (S)-2-(1-Aminoethyl)pyridine dihydrochloride; (S)-α-Methyl-2-pyridineethanamine dihydrochloride; (S)-Amphetamine, 2-pyridyl-, dihydrochloride; (S)-2-(1-Aminoethyl)pyridine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our 2-Pyridinemethanamine, A-Methyl-, Dihydrochloride, (As)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee reproducible results and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.