Description

(R)-1-Pyridin-3-Yl-Ethylamine 2Hcl CAS NO 40154-75-4 is a high-purity chiral amine derivative, specifically the dihydrochloride salt of the (R)-enantiomer. This compound is a critical chiral building block and ligand in asymmetric synthesis, valued for its ability to impart stereoselectivity in pharmaceutical and fine chemical manufacturing. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active pharmaceutical ingredients (APIs), catalysts, and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands used in transition metal catalysis to create stereogenic centers with high enantiomeric excess.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Academic & Process Chemistry Research: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.
• Fine Chemical Manufacturing: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(R)-1-Pyridin-3-Yl-Ethylamine 2Hcl
CAS No.	40154-75-4
Molecular Formula	C7H12N2·2HCl
Molecular Weight	209.11 g/mol
Synonyms	(R)-1-(3-Pyridyl)ethylamine dihydrochloride; (R)-α-Methyl-3-pyridinemethanamine dihydrochloride; (R)-1-(Pyridin-3-yl)ethan-1-amine dihydrochloride; (R)-3-(1-Aminoethyl)pyridine dihydrochloride; (R)-1-(3-Pyridinyl)ethylamine dihydrochloride; (R)-PEA·2HCl; (R)-(-)-1-(3-Pyridyl)ethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-Pyridin-3-Yl-Ethylamine 2Hcl is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.