Description

Diethyl(Methylsulfonylmethyl)Phosphonate is a versatile organophosphorus compound with a reactive methylsulfonylmethyl group, serving as a key building block in advanced organic synthesis. Its primary value lies in its role as a stabilized phosphonate anion equivalent, enabling the efficient construction of complex molecular frameworks under mild conditions. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to introduce critical functional groups and create novel carbon-carbon bonds.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex heterocycles and introducing phosphonate functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific phosphonate-based active ingredients.
• Horner-Wadsworth-Emmons (HWE) Reaction: Acts as a stabilized ylide precursor for the stereoselective synthesis of alkenes, a fundamental transformation in fine chemical manufacturing.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel phosphonate-based ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of flame retardants, polymer modifiers, and specialty materials where phosphonate groups enhance performance.
• Process Chemistry & Scale-up: Valued for its reliability and consistency in multi-kilogram to ton-scale production processes for high-value chemicals.

Basic Information

Product Name	Diethyl(Methylsulfonylmethyl)Phosphonate
CAS No.	40137-11-9
Molecular Formula	C6H15O5PS
Molecular Weight	230.22 g/mol
Synonyms	Diethyl (Methylsulfonylmethyl)phosphonate; (Methylsulfonylmethyl)phosphonic Acid Diethyl Ester; Diethyl P-Toluenesulfonylmethylphosphonate Analog; Diethyl (Methanesulfonylmethyl)phosphonate; Phosphonic acid, P-[(methylsulfonyl)methyl]-, diethyl ester; DESMP; Diethyl (methylsulfonyl)methylphosphonate
EINECS	Contact for details

Quality Control

Our Diethyl(Methylsulfonylmethyl)Phosphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for use in regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect reactivity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.