Description

Methyl 2-Chloronicotinate is a versatile chlorinated nicotinate ester derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a functionalized pyridine scaffold that enables the construction of complex molecules with high precision. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other heterocyclic active pharmaceutical ingredient (API) development.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require a functionalized pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Methyl 2-Chloronicotinate
CAS No.	40134-18-7
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	2-Chloronicotinic Acid Methyl Ester; Methyl 2-Chloropyridine-3-carboxylate; 3-Pyridinecarboxylic Acid, 2-Chloro-, Methyl Ester; 2-Chloro-3-methoxycarbonylpyridine; 2-Chloro-3-pyridinecarboxylic Acid Methyl Ester; 2-Chloronicotinic Acid, Methyl Ester; Methyl 2-Chloro-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloronicotinate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.