Description

2-[p-[Bis(2-Chloroethyl)Amino]Phenyl]-n-Ethylacetamide is a specialized nitrogen mustard derivative with significant potential in pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel therapeutic agents, particularly in oncology research. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of targeted chemotherapeutic candidates and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of experimental alkylating agents and anticancer drug candidates.
• Oncology Research: Used in preclinical studies to develop novel targeted therapies that leverage its nitrogen mustard pharmacophore.
• Biochemical Tool Compound: Serves as a reference standard and active agent in mechanistic studies of DNA alkylation and cell cycle inhibition.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies for optimizing potency and reducing off-target effects in drug discovery pipelines.
• Fine Chemical Synthesis: Intermediate for producing more complex, functionalized molecules with potential biological activity.
• Academic Research: Utilized in university and institutional labs for investigating new mechanisms of action and combination therapies.

Basic Information

Product Name	2-[p-[Bis(2-Chloroethyl)Amino]Phenyl]-n-Ethylacetamide
CAS No.	40068-20-0
Molecular Formula	C₁₄H₂₀Cl₂N₂O
Molecular Weight	303.23 g/mol
Synonyms	N-Ethyl-2-[4-[bis(2-chloroethyl)amino]phenyl]acetamide; 2-(4-[Bis(2-chloroethyl)amino]phenyl)-N-ethylacetamide; p-[N,N-Bis(2-chloroethyl)amino]phenethylacetamide; NSC 113942; U-9889; Mustard Phenacetamide Derivative; Chlorambucil Amide Analog
EINECS	Contact for details

Quality Control

Our 2-[p-[Bis(2-Chloroethyl)Amino]Phenyl]-n-Ethylacetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.