Description

β-Cyclohexyl-L-Alanine Methyl Ester is a chiral, non-proteinogenic amino acid derivative featuring a cyclohexyl side chain. This compound is a crucial building block (synthon) in organic synthesis, valued for its role in introducing constrained, lipophilic structural motifs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptidomimetics, active pharmaceutical ingredients (APIs), and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of peptide-based drugs and enzyme inhibitors.
• Peptidomimetic Research: Used to incorporate a rigid, hydrophobic cyclohexyl group into peptide backbones to enhance metabolic stability and binding affinity.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides with specific chiral activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective chemical transformations.
• Biochemical Research: Used in studies of enzyme-substrate interactions and structure-activity relationships (SAR).
• Material Science: Potential monomer for the synthesis of specialized polyamides or other functional polymers.

Basic Information

Item	Details
Product Name	β-Cyclohexyl-L-Alanine Methyl Ester
CAS No.	40056-18-6
Molecular Formula	C10H19NO2
Molecular Weight	185.26 g/mol
Synonyms	Methyl (2S)-2-Amino-3-cyclohexylpropanoate; L-β-Cyclohexylalanine Methyl Ester; (S)-Methyl 2-Amino-3-cyclohexylpropanoate; Methyl L-β-Cyclohexylalaninate; (S)-2-Amino-3-cyclohexylpropionic Acid Methyl Ester; β-Cyclohexyl-L-alanine Methyl Ester; NSC 334907; Methyl (S)-2-amino-3-cyclohexylpropionate
EINECS	Contact for details

Quality Control

Our β-Cyclohexyl-L-Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and specific tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.