Description

3-tert-Butoxy-3-Oxopropanoic Acid CAS NO 40052-13-9 is a versatile organic acid ester, specifically a tert-butyl ester of malonic acid semialdehyde, valued as a key synthetic intermediate in advanced organic synthesis. Its structure makes it a crucial building block for introducing protected aldehyde and carboxylic acid functionalities, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for API development and fine chemical production.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring malonate or β-ketoester frameworks.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its reactive sites allow for selective derivatization.
• Fine Chemical Manufacturing: Acts as a building block for dyes, pigments, flavors, and fragrances that require specific carboxylic acid ester functionalities.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the synthesis of specialty polymers and resins with tailored properties.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for methodologies like Knoevenagel condensations and Michael additions.
• Peptide Mimetics: Used in the design and synthesis of peptide analogs and enzyme inhibitors due to its bifunctional nature.

Basic Information

Product Name	3-tert-Butoxy-3-Oxopropanoic Acid
CAS No.	40052-13-9
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	3-(tert-Butoxy)-3-oxopropanoic acid; 2-(tert-Butoxycarbonyl)acetic acid; Malonaldehyde acid tert-butyl ester; tert-Butyl hydrogen malonate; 3-tert-Butoxy-3-oxopropanoic acid; 3-tert-Butoxycarbonylpropanoic acid; (tert-Butoxycarbonyl)acetic acid; BOC-acetic acid
EINECS	Contact for details

Quality Control

Our 3-tert-Butoxy-3-Oxopropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clientele. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.