Description

Piperidine-4-Carboxylic Acid (2-Hydroxy-1,1-Dimethyl-Ethyl)-Amide is a high-value piperidine derivative and a versatile chiral building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry and functional groups are critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the piperidine moiety contributes to biological efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D: A valuable compound for medicinal chemistry research, process development, and exploring new synthetic methodologies in laboratory settings.

Basic Information

Product Name	Piperidine-4-Carboxylic Acid (2-Hydroxy-1,1-Dimethyl-Ethyl)-Amide
CAS No.	40051-33-0
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	4-Piperidinecarboxamide, N-(2-hydroxy-1,1-dimethylethyl)-; 2-Hydroxy-1,1-dimethylethyl 4-piperidinecarboxamide; (2-Hydroxy-1,1-dimethylethyl)carbamoylpiperidine; 1-(2-Hydroxy-2-methylpropyl)aminocarbonyl-4-piperidine; 4-Carbamoylpiperidine, N-(2-hydroxy-tert-butyl) derivative; tert-Butyl(2-hydroxy) 4-piperidinecarboxamide; (RS)-N-(2-Hydroxy-1,1-dimethylethyl)isonipecotamide
EINECS	Contact for details

Quality Control

Our Piperidine-4-Carboxylic Acid (2-Hydroxy-1,1-Dimethyl-Ethyl)-Amide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.