Description

S-(2-Methoxy-2-Oxoethyl)-n-(Trifluoroacetyl)-L-Cysteine Methyl Ester is a high-purity, protected cysteine derivative designed for advanced synthetic chemistry. This compound serves as a critical chiral building block, enabling the controlled introduction of cysteine moieties into complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for applications in peptide synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for cysteine-containing peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected cysteine residue, preventing unwanted side reactions during chain assembly.
• Medicinal Chemistry & Drug Discovery: Enables structure-activity relationship (SAR) studies by facilitating the precise modification of peptide-based drug candidates.
• Bioconjugation Chemistry: Acts as a precursor for creating specialized linkers or handles for protein and antibody-drug conjugate (ADC) development.
• Chemical Biology Research: Employed in the synthesis of probes and tools for studying enzyme mechanisms and protein-protein interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	S-(2-Methoxy-2-Oxoethyl)-n-(Trifluoroacetyl)-L-Cysteine Methyl Ester
CAS No.	40027-86-9
Molecular Formula	C9H12F3NO5S
Molecular Weight	303.26 g/mol
Synonyms	N-Trifluoroacetyl-S-(carboxymethyl)-L-cysteine Methyl Ester; L-Cysteine, S-(carboxymethyl)-N-(trifluoroacetyl)-, methyl ester; Methyl N-(Trifluoroacetyl)-S-(carboxymethyl)-L-cysteinate; S-Carboxymethyl-N-trifluoroacetyl-L-cysteine Methyl Ester; N-TFA-S-CM-L-Cysteine-OMe; Protected L-Cysteine Derivative; Cysteine Synthon
EINECS	Contact for details

Quality Control

Our S-(2-Methoxy-2-Oxoethyl)-n-(Trifluoroacetyl)-L-Cysteine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.