Description

Pimetine Hydrochloride is a high-purity pharmaceutical intermediate and research chemical with significant importance in medicinal chemistry. Its value lies in its role as a key building block for the synthesis of more complex active pharmaceutical ingredients (APIs) and for pharmacological research. This compound is primarily needed by pharmaceutical manufacturers, biotechnology research firms, and academic institutions engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used as a standard or building block in structure-activity relationship (SAR) studies to optimize drug efficacy and safety profiles.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products.
• Biochemical Research: Utilized in in-vitro and in-vivo studies to investigate specific biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Pimetine Hydrochloride
CAS No.	4991-68-8
Molecular Formula	C16H24N2O2•HCl
Molecular Weight	312.84 g/mol
Synonyms	Pimetine HCl; 1-(2,6-Dimethylphenoxy)-2-(1-pyrrolidinyl)ethane Hydrochloride; Pimetine Monohydrochloride; Pimetine Hydrochloride Salt; 2-(1-Pyrrolidinyl)-1-(2,6-xylyloxy)ethane Hydrochloride; 1-(2,6-Dimethylphenoxy)-2-(pyrrolidin-1-yl)ethane hydrochloride
EINECS	Contact for details

Quality Control

Our Pimetine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all test results against agreed specifications is provided with each shipment. We can supply material compliant with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.