Description

Oestradiol 17-Heptanoate CAS NO 4956-37-0 is a long-acting ester derivative of the natural estrogen, estradiol. This compound is valued for its enhanced stability and prolonged pharmacological activity compared to the parent hormone, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical and life science research sectors for the development of hormone replacement therapies, veterinary medicines, and controlled-release formulations.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of long-acting estrogenic drugs and hormone replacement therapy (HRT) products.
• Veterinary Medicine: Used in the formulation of long-acting estrus synchronization and fertility treatments for livestock and companion animals.
• Research & Development: Serves as a reference standard and biochemical tool in endocrinology research, studying estrogen receptor activity and metabolic pathways.
• Controlled-Release Formulations: Utilized in the development of depot injections and implantable devices due to its esterified structure providing sustained release.
• API Synthesis: An important building block in the multi-step synthesis of more complex steroidal active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Oestradiol 17-Heptanoate
CAS No.	4956-37-0
Molecular Formula	C25H36O3
Molecular Weight	384.56 g/mol
Synonyms	Estradiol 17-Heptanoate; Estradiol Enanthate; 17β-Estradiol 17-heptanoate; Oestradiol Enanthate; NSC 17591; Estr-1,3,5(10)-triene-3,17β-diol 17-heptanoate; 3,17β-Dihydroxyestra-1,3,5(10)-trien-17-yl heptanoate
EINECS	225-590-1

Quality Control

Our Oestradiol 17-Heptanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and specific tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP and relevant pharmacopeial guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.