Description

Estra-1,3,5(10)-Triene-3,17Beta-Diol 17-Acetate 3-Benzoate is a high-purity steroid derivative, specifically a synthetic estrogen ester. This compound is valued for its role as a key pharmaceutical intermediate in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development and production of hormonal therapies and related compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Hormone Research: Used in biochemical and pharmacological research to study estrogen receptor activity and metabolic pathways.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Precursor for Conjugated Estrogens: Potential use in the development of complex estrogen formulations for therapeutic applications.

Basic Information

Product Name	Estra-1,3,5(10)-Triene-3,17Beta-Diol 17-Acetate 3-Benzoate
CAS No.	4954-17-0
Molecular Formula	C27H32O4
Molecular Weight	420.55 g/mol
Synonyms	Estradiol 3-Benzoat 17-Acetate; 3,17β-Dihydroxyestra-1,3,5(10)-trien-3-yl benzoate 17-acetate; 17β-Estradiol 3-benzoate 17-acetate; Estradiol Benzoate Acetate; NSC 121773; 3-Benzoyloxyestra-1,3,5(10)-trien-17β-ol 17-acetate
EINECS	225-582-4

Quality Control

Our Estra-1,3,5(10)-Triene-3,17Beta-Diol 17-Acetate 3-Benzoate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC, IR, and NMR to ensure identity, purity, and conformity to stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.