Description

Methyl 3-Bromocyclobutane-1-Carboxylate is a versatile brominated cyclobutane ester, serving as a crucial synthetic intermediate in advanced organic chemistry. Its unique strained-ring structure and reactive bromine substituent make it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing constrained cyclobutane rings for improved metabolic stability and potency.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the cyclobutane moiety can impart unique biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Monomer: Potential monomer for the synthesis of specialty polymers with unique thermal and mechanical properties derived from the strained ring system.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying biological systems and protein interactions.
• Academic & Industrial R&D: Fundamental reagent in methodological organic chemistry research for studying ring-opening, functionalization, and cycloaddition reactions of strained carbocycles.

Basic Information

Product Name	Methyl 3-Bromocyclobutane-1-Carboxylate
CAS No.	4935-00-6
Molecular Formula	C7H11BrO2
Molecular Weight	207.07 g/mol
Synonyms	3-Bromocyclobutane-1-carboxylic acid methyl ester; Methyl 3-bromocyclobutanecarboxylate; 3-Bromocyclobutanecarboxylic Acid Methyl Ester; 1-Carbomethoxy-3-bromocyclobutane; Methyl ester of 3-bromocyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques including GC, HPLC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a quality management system to ensure traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.