Description

Proline, 1-Ethenyl-5-Oxo-, Methyl Ester (9Ci) is a specialized proline derivative with a reactive vinyl group, making it a valuable chiral building block for advanced organic synthesis. This compound is crucial for researchers and manufacturers developing novel pharmaceuticals and bioactive molecules, particularly in the fields of peptidomimetics and enzyme inhibitors. It serves the needs of fine chemical producers, pharmaceutical R&D laboratories, and academic institutions focused on asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, especially protease inhibitors and other targeted therapeutics.
• Peptidomimetics Research: Used to construct non-natural amino acid scaffolds that mimic peptide structures for enhanced metabolic stability and bioavailability.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in enantioselective transformations.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and protein-protein interactions due to its reactive handle.
• Agrochemical Synthesis: Intermediate in the development of advanced, chiral active ingredients for crop protection.
• Academic & R&D: Fundamental building block in organic chemistry research for methodology development and novel compound library generation.

Basic Information

Product Name	Proline, 1-Ethenyl-5-Oxo-, Methyl Ester (9Ci)
CAS No.	4931-67-3
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	1-Vinyl-5-oxoproline methyl ester; Methyl 1-ethenyl-5-oxo-L-prolinate; Methyl 1-vinyl-5-oxo-L-prolinate; 5-Oxo-1-vinylproline methyl ester; (S)-1-Ethenyl-5-oxopyrrolidine-2-carboxylic acid methyl ester; L-Proline, 1-ethenyl-5-oxo-, methyl ester; 1-Ethenyl-5-oxo-L-proline methyl ester
EINECS	Contact for details

Quality Control

Our Proline, 1-Ethenyl-5-Oxo-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.