Description

3-(Bromomethyl)Pyridine Hydrobromide is a versatile brominated pyridine derivative, a crucial building block in advanced organic synthesis. Its primary value lies in its dual functionality, serving as an effective alkylating agent and a protected pyridine precursor for constructing complex molecular architectures. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to create active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the pyridine moiety is a common structural feature.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and protein interactions.
• Material Science: Building block for creating functionalized polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: Useful substrate in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce functionalized pyridine units.

Basic Information

Product Name	3-(Bromomethyl)Pyridine Hydrobromide
CAS No.	4916-55-6
Molecular Formula	C6H7Br2N
Molecular Weight	252.94 g/mol
Synonyms	3-Pyridinemethanol, α-bromo-, hydrobromide; (3-Pyridyl)methyl bromide hydrobromide; 3-(Bromomethyl)pyridine HBr; 3-Picolyl bromide hydrobromide; α-Bromo-3-picoline hydrobromide; 3-Bromomethylpyridine hydrobromide; Pyridine, 3-(bromomethyl)-, hydrobromide
EINECS	225-540-6

Quality Control

Our 3-(Bromomethyl)Pyridine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.