Description

Methyl 4-Bromobutyrate is a versatile brominated ester building block, essential for introducing the 4-bromobutyl moiety into complex molecular frameworks. Its primary value lies in its reactivity as an alkylating agent and as a key intermediate in multi-step organic synthesis, enabling the construction of pharmaceuticals, agrochemicals, and advanced materials. This compound is particularly critical for R&D chemists and process development scientists in the pharmaceutical, fine chemical, and material science industries seeking reliable, high-purity intermediates for nucleophilic substitution and cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a butyl chain linker or terminal functionalization.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators that incorporate bromoalkyl segments.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating brominated organic semiconductors and liquid crystal molecules.
• Polymer Modification: Employed to introduce bromine functional groups into polymer backbones for further chemical modification or as flame retardant precursors.
• Cross-Coupling Reactions: Acts as an electrophile in reactions such as Suzuki, Heck, and Negishi couplings to form carbon-carbon bonds.
• Organic Synthesis Reagent: Utilized in laboratories for the preparation of γ-amino butyric acid (GABA) analogs, heterocycles, and other specialty organic compounds.

Basic Information

Product Name	Methyl 4-Bromobutyrate
CAS No.	4897-84-1
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	4-Bromobutanoic Acid Methyl Ester; Methyl 4-Bromobutanoate; γ-Bromobutyric Acid Methyl Ester; Methyl γ-Bromobutyrate; Butanoic acid, 4-bromo-, methyl ester; NSC 9376; Methyl ester of 4-bromobutyric acid
EINECS	225-516-9

Quality Control

Our Methyl 4-Bromobutyrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support customer audits and regulatory documentation needs for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Refractive Index (n20/D)	1.4580 - 1.4620
Density (g/mL, 20°C)	1.390 - 1.410
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.