Description

n-[(Benzyloxy)Carbonyl]Glycine 2,4,5-Trichlorophenyl Ester is a specialized, high-purity chemical building block used in advanced organic synthesis. This compound matters because it serves as a key activated ester intermediate, enabling the efficient and selective formation of peptide bonds under mild conditions. It is primarily needed by research institutions and pharmaceutical manufacturers for the development of novel peptides, peptidomimetics, and other bioactive molecules, where precise molecular assembly is critical.

Application

• Peptide Synthesis: As an activated ester for the coupling of Z-protected glycine in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: A crucial building block in the research and production of active pharmaceutical ingredients (APIs) with peptide backbones.
• Bioconjugation: Used to attach glycine or other moieties to biomolecules like proteins or antibodies for drug delivery and diagnostic applications.
• Chemical Biology Research: Employed in the synthesis of probes, inhibitors, and other tools for studying biological processes at the molecular level.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	n-[(Benzyloxy)Carbonyl]Glycine 2,4,5-Trichlorophenyl Ester
CAS No.	4865-50-3
Molecular Formula	C16H12Cl3NO4
Molecular Weight	388.63 g/mol
Synonyms	Z-Gly-OPcp; Z-Glycine 2,4,5-Trichlorophenyl Ester; N-Carbobenzoxyglycine 2,4,5-Trichlorophenyl Ester; N-(Benzyloxycarbonyl)glycine 2,4,5-Trichlorophenyl Ester; Cbz-Gly-OPcp; Benzyl N-(2,4,5-Trichlorophenoxycarbonyl)glycinate; Glycine, N-[(phenylmethoxy)carbonyl]-, 2,4,5-trichlorophenyl ester
EINECS	Contact for details

Quality Control

Our n-[(Benzyloxy)Carbonyl]Glycine 2,4,5-Trichlorophenyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.