Description

6-o-Acetyl-1,2:3,4-Di-o-Isopropylidene-α-D-Galactopyranose CAS NO 4860-78-0 is a key protected monosaccharide derivative, specifically an acetylated and isopropylidene-protected form of D-galactose. This compound is a critical chiral intermediate and building block in sophisticated organic synthesis, valued for its defined stereochemistry and reactivity. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the production of complex carbohydrates, nucleoside analogs, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel antiviral, anticancer, and antibiotic drugs, particularly nucleoside-based therapeutics.
• Carbohydrate Chemistry Research: Serves as a protected galactose donor in the synthesis of oligosaccharides, glycoconjugates, and glycomimetics for biological studies.
• Glycobiology & Diagnostics: Used in the development of carbohydrate-based probes, vaccines, and diagnostic reagents.
• Fine Chemical Synthesis: Acts as a chiral precursor for the preparation of flavors, fragrances, and specialty chemicals requiring specific sugar motifs.
• Academic & Industrial R&D: Essential for method development and exploratory synthesis in medicinal chemistry and chemical biology laboratories.

Basic Information

Product Name	6-o-Acetyl-1,2:3,4-Di-o-Isopropylidene-α-D-Galactopyranose
CAS No.	4860-78-0
Molecular Formula	C14H22O7
Molecular Weight	302.32 g/mol
Synonyms	1,2:3,4-Di-O-Isopropylidene-6-O-acetyl-α-D-galactopyranose; 6-O-Acetyl-1,2:3,4-di-O-isopropylidene-α-D-galactose; 6-O-Acetyl-1,2:3,4-di-O-(1-methylethylidene)-α-D-galactopyranose; 6-Acetyl-1,2:3,4-diisopropylidene galactose; α-D-Galactopyranose, 6-acetyl-1,2:3,4-di-O-(1-methylethylidene)-; Diacetone galactose 6-acetate; Protected D-Galactose Derivative
EINECS	225-480-5

Quality Control

Our production of 6-o-Acetyl-1,2:3,4-Di-o-Isopropylidene-α-D-Galactopyranose adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-75° to -85° (c=1 in CHCl3)
Melting Point	98°C - 102°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.