Description

n-[(Benzyloxy)Carbonyl]Glycine Pentachlorophenyl Ester is a specialized peptide coupling reagent and a protected amino acid derivative. This compound is critical for facilitating efficient amide bond formation in complex organic synthesis, particularly in peptide chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents and biochemical tools.

Application

• Peptide Synthesis: As an activated ester for the efficient coupling of glycine and other amino acids in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: A key building block in the research and production of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Used for labeling proteins, antibodies, and other biomolecules by introducing functional handles.
• Organic Synthesis Reagent: Employed in the synthesis of complex organic molecules requiring selective amide bond formation under mild conditions.
• Biochemical Research: Serves as a tool compound for studying enzyme mechanisms and developing enzyme inhibitors.
• Material Science: Potential monomer or cross-linker in the development of specialized polymers and biomaterials.

Basic Information

Product Name	n-[(Benzyloxy)Carbonyl]Glycine Pentachlorophenyl Ester
CAS No.	4824-12-8
Molecular Formula	C16H10Cl5NO4
Molecular Weight	463.52 g/mol
Synonyms	Z-Gly-OPcp; Cbz-Glycine Pentachlorophenyl Ester; Benzyloxycarbonylglycine Pentachlorophenyl Ester; N-Carbobenzoxyglycine Pentachlorophenyl Ester; N-(Benzyloxycarbonyl)glycine 2,3,4,5,6-Pentachlorophenyl Ester; Pentafluorophenyl Ester of Z-Glycine (common misnomer); Glycine, N-[(phenylmethoxy)carbonyl]-, 2,3,4,5,6-pentachlorophenyl ester; NSC 334903
EINECS	Contact for details

Quality Control

Our n-[(Benzyloxy)Carbonyl]Glycine Pentachlorophenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.