Description

Isocyanatocyclopropane CAS NO 4747-72-2 is a highly reactive, small-ring isocyanate building block used in advanced organic synthesis. Its strained cyclopropane ring and isocyanate functional group make it a valuable precursor for constructing complex molecular architectures with unique three-dimensional properties. This specialty chemical is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring a rigid, three-membered ring structure to modulate biological activity.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, where the cyclopropane moiety can enhance stability and efficacy.
• Polymer & Material Science: Acts as a cross-linking agent or monomer for synthesizing specialty polymers, polyurethanes, and coatings with tailored mechanical and chemical resistance properties.
• Chemical Research: Employed in academic and industrial R&D laboratories for [1,3]-dipolar cycloaddition reactions and other cycloadditions to create novel heterocyclic compounds.
• Ligand & Catalyst Development: Utilized to synthesize novel ligands and organocatalysts that incorporate the sterically constrained cyclopropane framework.

Basic Information

Product Name	Isocyanatocyclopropane
CAS No.	4747-72-2
Molecular Formula	C4H5NO
Molecular Weight	83.09 g/mol
Synonyms	Cyclopropyl isocyanate; Cyclopropane, isocyanato-; Isocyanic acid, cyclopropyl ester; 1-Isocyanatocyclopropane; Cyclopropanyl isocyanate
EINECS	225-257-9

Quality Control

Our Isocyanatocyclopropane is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maximize stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.