Description

Spiro[4.5]Decan-1-One CAS NO 4728-91-0 is a high-purity, specialized spirocyclic ketone building block of significant interest in advanced organic synthesis. Its unique bridged bicyclic structure makes it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fragrance industries, where it serves as a key precursor for novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those requiring rigid, three-dimensional frameworks to enhance binding affinity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its spiro structure can contribute to unique modes of action and environmental profiles.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthetic musk compounds and other specialty aroma chemicals, imparting specific olfactory characteristics.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials that benefit from its defined stereochemistry.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including catalysis, ring-forming reactions, and stereoselective synthesis.

Basic Information

Product Name	Spiro[4.5]Decan-1-One
CAS No.	4728-91-0
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Synonyms	Spiro[4.5]decan-1-one; 1-Oxaspiro[4.5]decane; 1-Oxaspiro(4.5)decane; Spiro(4.5)decan-1-one; Spiro-4,5-decan-1-one; 1-Oxaspiro[4,5]decane; Spirodecanone; Contact for additional trade names.
EINECS	225-214-8

Quality Control

Our Spiro[4.5]Decan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.