Description

17A-Ethynylestriol is a synthetic steroidal estrogen derivative, recognized for its potent biological activity and structural specificity. This compound is of significant value in pharmaceutical research and development, particularly for its role as a key intermediate or reference standard in the synthesis of novel hormonal agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in endocrinology, steroid chemistry, and drug discovery programs. The material is handled under controlled conditions to ensure its integrity for sensitive applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathways for advanced steroidal drugs and hormonal therapies.
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor binding, metabolism, and signal transduction pathways.
• Reference Material: Employed in analytical laboratories for method development, validation, and quality control testing of related estrogenic compounds.
• Academic & R&D: Facilitates chemical research in university and institutional settings focused on medicinal chemistry and steroid analog development.

Basic Information

Product Name	17A-Ethynylestriol
CAS No.	4717-40-2
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,16α,17β-triol; Ethynylestriol; 17α-Ethynylestra-1,3,5(10)-triene-3,16α,17β-triol; NSC 121773; 17α-Ethynyl-1,3,5(10)-estratriene-3,16α,17β-triol
EINECS	Contact for details

Quality Control

Our 17A-Ethynylestriol is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development purposes. Certificates of Analysis (COA) detailing specific test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.