Description

(7-Chloro-2,3-Dihydro-2-Oxo-5-Phenyl-1H-Benzo-1,4-Diazepin-3-Yl) Hydrogen Succinate is a high-purity pharmaceutical intermediate and active metabolite of the anxiolytic drug diazepam. This compound is critical for research and development in neuropharmacology and for the synthesis of advanced benzodiazepine derivatives. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on central nervous system (CNS) drug discovery and metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis and research of benzodiazepine-class active pharmaceutical ingredients (APIs).
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical methods (e.g., HPLC, LC-MS) for pharmacokinetic and drug metabolism studies of diazepam and related compounds.
• Preclinical Research: Employed in neurological and pharmacological research to study the mechanisms, efficacy, and safety profiles of benzodiazepine metabolites.
• Quality Control: Serves as a certified reference material (CRM) for the identification and quantification of impurities in diazepam API manufacturing.
• Chemical Synthesis: Utilized in medicinal chemistry for the design and development of novel therapeutic agents targeting GABA-A receptors.

Basic Information

Product Name	(7-Chloro-2,3-Dihydro-2-Oxo-5-Phenyl-1H-Benzo-1,4-Diazepin-3-Yl) Hydrogen Succinate
CAS No.	4700-56-5
Molecular Formula	C19H15ClN2O5
Molecular Weight	386.79 g/mol
Synonyms	Nordazepam Hydrogen Succinate; Nordazepam Hemisuccinate; 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 3-hemisuccinate; Desmethyldiazepam Hemisuccinate; Nordiazepam Hemisuccinate; 1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-, 3-(3-carboxypropanoate); Demethyldiazepam Hemisuccinate
EINECS	Contact for details

Quality Control

Our (7-Chloro-2,3-Dihydro-2-Oxo-5-Phenyl-1H-Benzo-1,4-Diazepin-3-Yl) Hydrogen Succinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.