Description

Azidotrimethylsilane is a versatile organosilicon reagent featuring a reactive azide group. This compound is a key building block in organic synthesis, enabling the efficient introduction of azide functionality for subsequent transformations like click chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel compounds and polymers.

Application

• Pharmaceutical Intermediates: A crucial reagent for synthesizing azide-containing bioactive molecules and drug candidates.
• Click Chemistry: Used as a precursor for generating organic azides in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Polymer Modification: Employed to functionalize polymers and surfaces with azide groups for advanced material development.
• Peptide Synthesis: Facilitates the modification of peptides and proteins via azide-alkyne ligation strategies.
• Agrochemical Synthesis: Serves as a building block in the production of novel herbicides, fungicides, and insecticides.
• Cross-coupling Reactions: Acts as a reagent in palladium-catalyzed cross-coupling for C-N bond formation.

Basic Information

Product Name	Azidotrimethylsilane
CAS No.	4648-54-8
Molecular Formula	C3H9N3Si
Molecular Weight	115.21 g/mol
Synonyms	Trimethylsilyl azide; TMS azide; TMSN3; Azidotrimethylsilane; (Azidomethyl)dimethylsilane; Azidotrimethylsilicon; Trimethylsilyl azide (TMSN3); N3Si(CH3)3
EINECS	225-081-0

Quality Control

Our Azidotrimethylsilane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and titration, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.