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2-Bromo-6-Ethoxy Pyridine CAS NO 4645-11-8


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CAS No.:4645-11-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-6-Ethoxy Pyridine is a versatile halogenated pyridine derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of the bromine and ethoxy groups, which enable selective functionalization for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its reactivity for creating diverse heterocyclic systems.
  • Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
  • Material Science Research: Employed in the creation of functionalized organic molecules for electronic materials, organic light-emitting diodes (OLEDs), and liquid crystals.
  • Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine substituent.
  • Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name 2-Bromo-6-Ethoxy Pyridine
CAS No. 4645-11-8
Molecular Formula C7H8BrNO
Molecular Weight 202.05 g/mol
Synonyms 6-Ethoxy-2-bromopyridine; 2-Bromo-6-ethoxypyridine; 2-Bromo-6-ethoxy-pyridine; Pyridine, 2-bromo-6-ethoxy-; 4645-11-8; 2-Br-6-EtO-Py; 6-Ethoxy-2-bromo-pyridine
EINECS Contact for details

Quality Control

Our 2-Bromo-6-Ethoxy Pyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Melting Point Contact for details
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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