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5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose CAS NO 4613-64-3
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CAS No.:4613-64-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose is a key protected sugar intermediate, specifically a benzoylated and isopropylidene-protected derivative of a deoxy ribo-hexofuranose. This compound is critically important for its role in the stereoselective synthesis of complex nucleoside analogs and other biologically active carbohydrate derivatives. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and novel therapeutic oligonucleotides.
Application
- Nucleoside & Nucleotide Synthesis: Serves as a crucial chiral building block for the preparation of modified nucleosides used in antiviral and anticancer research.
- Carbohydrate Chemistry: Used as a protected intermediate in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
- Pharmaceutical Intermediates: A key starting material in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting viral infections.
- Biochemical Research: Employed in studies exploring enzyme mechanisms, metabolic pathways, and the structure-activity relationships of sugar-based compounds.
- Process Development: Used for scaling up synthetic routes in process chemistry for pilot and commercial-scale manufacturing.
Basic Information
| Product Name | 5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose |
| CAS No. | 4613-64-3 |
| Molecular Formula | C24H26O7 |
| Molecular Weight | 426.46 g/mol |
| Synonyms | 1,2-O-Isopropylidene-3-deoxy-5,6-di-O-benzoyl-α-D-ribo-hexofuranose; 3-Deoxy-1,2-O-isopropylidene-5,6-di-O-benzoyl-α-D-ribo-hexofuranose; 5,6-Di-O-benzoyl-1,2-O-isopropylidene-3-deoxy-α-D-ribo-hexofuranose; 3-Deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose derivative; Protected 3-deoxy-D-ribo-hexofuranose |
| EINECS | Contact for details |
Quality Control
Our 5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed in a dry environment to prevent moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Specific Rotation | Contact for details |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | < 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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