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5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose CAS NO 4613-64-3


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CAS No.:4613-64-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose is a key protected sugar intermediate, specifically a benzoylated and isopropylidene-protected derivative of a deoxy ribo-hexofuranose. This compound is critically important for its role in the stereoselective synthesis of complex nucleoside analogs and other biologically active carbohydrate derivatives. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and novel therapeutic oligonucleotides.

Application

  • Nucleoside & Nucleotide Synthesis: Serves as a crucial chiral building block for the preparation of modified nucleosides used in antiviral and anticancer research.
  • Carbohydrate Chemistry: Used as a protected intermediate in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
  • Pharmaceutical Intermediates: A key starting material in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting viral infections.
  • Biochemical Research: Employed in studies exploring enzyme mechanisms, metabolic pathways, and the structure-activity relationships of sugar-based compounds.
  • Process Development: Used for scaling up synthetic routes in process chemistry for pilot and commercial-scale manufacturing.

Basic Information

Product Name 5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose
CAS No. 4613-64-3
Molecular Formula C24H26O7
Molecular Weight 426.46 g/mol
Synonyms 1,2-O-Isopropylidene-3-deoxy-5,6-di-O-benzoyl-α-D-ribo-hexofuranose; 3-Deoxy-1,2-O-isopropylidene-5,6-di-O-benzoyl-α-D-ribo-hexofuranose; 5,6-Di-O-benzoyl-1,2-O-isopropylidene-3-deoxy-α-D-ribo-hexofuranose; 3-Deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose derivative; Protected 3-deoxy-D-ribo-hexofuranose
EINECS Contact for details

Quality Control

Our 5-O,6-o-Dibenzoyl-1-O,2-o-Isopropylidene-3-Deoxy-α-D-Ribo-Hexofuranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed in a dry environment to prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Specific Rotation Contact for details
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals < 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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