Description

2-Chloro-4,6-Diphenylnicotinonitrile is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a chlorinated pyridine ring flanked by phenyl groups, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic core.
• Material Science Research: Serves as a precursor for creating specialized ligands, organic semiconductors, or liquid crystal materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in heterocyclic and cross-coupling chemistry.
• Custom Synthesis: A starting point for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	2-Chloro-4,6-Diphenylnicotinonitrile
CAS No.	4604-05-1
Molecular Formula	C18H11ClN2
Molecular Weight	290.75 g/mol
Synonyms	2-Chloro-4,6-diphenyl-3-pyridinecarbonitrile; 2-Chloro-4,6-diphenyl-3-cyanopyridine; 3-Cyano-2-chloro-4,6-diphenylpyridine; Nicotinonitrile, 2-chloro-4,6-diphenyl-; 4604-05-1; 2-Chloro-4,6-diphenylnicotinonitrile; 2-Chloro-4,6-diphenylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,6-Diphenylnicotinonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a Certificate of Analysis (COA) with every shipment, detailing batch-specific results. Our quality system is designed to meet the stringent requirements of R&D and pre-clinical development applications, ensuring consistency and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.