Description

2-Methyl-3-Hydroxy-4-Hydroxymethyl-5-Carboxypyridine Lactone is a high-purity pyridine derivative with a complex, functionalized structure, making it a valuable intermediate for advanced chemical synthesis. Its significance lies in its role as a key building block for pharmaceuticals, fine chemicals, and specialized research compounds, offering precise molecular architecture for downstream applications. This product is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic pathways.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialized catalysts, ligands, and other high-value fine chemicals.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway research.
• Vitamin B6 Analog Synthesis: Acts as a key intermediate in the production of pyridoxine (Vitamin B6) analogs and derivatives.
• Material Science: Potential use in the synthesis of functional polymers and advanced organic materials.

Basic Information

Product Name	2-Methyl-3-Hydroxy-4-Hydroxymethyl-5-Carboxypyridine Lactone
CAS No.	4543-56-0
Molecular Formula	C8H7NO4
Molecular Weight	181.15 g/mol
Synonyms	5-Carboxy-2-methyl-3-hydroxy-4-hydroxymethylpyridine Lactone; 3-Hydroxy-2-methyl-4-hydroxymethyl-5-carboxypyridine Lactone; Pyridoxine Lactone; Vitamin B6 Lactone; 2-Methyl-3-hydroxy-4-(hydroxymethyl)-5-pyridinecarboxylic acid δ-lactone; 5-Carboxy-3-hydroxy-2-methyl-4-pyridinemethanol Lactone; 4-Pyridinemethanol, 5-carboxy-3-hydroxy-2-methyl-, δ-lactone
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-Hydroxy-4-Hydroxymethyl-5-Carboxypyridine Lactone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.