Description

Methyl Diexo-3-Amino-7-Oxa-Bicyclo[2.2.1]Heptane-2-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic oxa-norbornane scaffold. This compound is critical for the synthesis of complex molecules, offering a rigid, three-dimensional structure that is highly valuable in modern drug discovery. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

This specialized intermediate serves as a key building block in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core scaffold for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides with unique modes of action.
• Chiral Auxiliary & Ligand Precursor: Serves as a starting material for synthesizing chiral catalysts and ligands used in asymmetric synthesis.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in research laboratories.
• Peptidomimetics Development: Its constrained structure is utilized to create conformationally restricted peptide analogs.

Basic Information

Product Name	Methyl Diexo-3-Amino-7-Oxa-Bicyclo[2.2.1]Heptane-2-Carboxylate Hydrochloride
CAS No.	4505-16-2
Molecular Formula	C8H12ClNO3
Molecular Weight	205.64 g/mol
Synonyms	Methyl 3-Amino-7-oxabicyclo[2.2.1]heptane-2-carboxylate hydrochloride; 7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, methyl ester, hydrochloride, endo-; Methyl 3-amino-7-oxabicyclo[2.2.1]heptane-2-carboxylate HCl; 3-Amino-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid methyl ester hydrochloride; endo-Methyl 3-amino-7-oxabicyclo[2.2.1]heptane-2-carboxylate hydrochloride; (1R,2S,3S,4R)-Methyl 3-amino-7-oxabicyclo[2.2.1]heptane-2-carboxylate hydrochloride (for specific stereoisomer).
EINECS	Contact for details

Quality Control

Our Methyl Diexo-3-Amino-7-Oxa-Bicyclo[2.2.1]Heptane-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.