Description

3,4,6-Tri-o-Acetyl-B-D-Mannopyranose1,2-(Methylorthoacetate) is a key protected carbohydrate intermediate, specifically a mannose derivative with acetyl and orthoacetate protecting groups. This compound is critical for synthetic chemists as it provides a versatile and reactive scaffold for the controlled synthesis of complex oligosaccharides, glycoconjugates, and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, glycobiology research, and the development of novel therapeutics and diagnostics.

Application

• Glycosylation Reactions: Serves as a crucial mannosyl donor or acceptor in the synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: A building block for creating glycoproteins, glycolipids, and other biologically active conjugates for immunological studies.
• Chemical Biology Probes: Employed in the creation of labeled sugars and probes to study carbohydrate-protein interactions and metabolic pathways.
• Standard Reference Material: Acts as a high-purity analytical standard for quality control in carbohydrate chemistry and related research fields.
• Enzyme Substrate Studies: Used to investigate the activity and specificity of glycosidases and glycosyltransferases.

Basic Information

Product Name	3,4,6-Tri-o-Acetyl-B-D-Mannopyranose1,2-(Methylorthoacetate)
CAS No.	4435-05-6
Molecular Formula	C15H22O10
Molecular Weight	362.33 g/mol
Synonyms	1,2-O-(1-Methoxyethylidene)-3,4,6-tri-O-acetyl-α-D-mannopyranose; Methyl 3,4,6-tri-O-acetyl-1,2-O-(1-methoxyethylidene)-α-D-mannopyranoside; 3,4,6-Tri-O-acetyl-1,2-O-(1-methoxyethylidene)-α-D-mannopyranose; 1,2-O-Methylorthoacetyl-3,4,6-tri-O-acetyl-α-D-mannopyranose; Mannose 1,2-(methyl orthoacetate) 3,4,6-triacetate; Protected Mannose Orthoester; α-D-Mannopyranose, 3,4,6-triacetate 1,2-(methyl orthoacetate)
EINECS	Contact for details

Quality Control

Every batch of our 3,4,6-Tri-o-Acetyl-B-D-Mannopyranose1,2-(Methylorthoacetate) is produced and tested under strict quality management protocols. We ensure high purity and consistency suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC/NMR), and impurity profiles is provided with each shipment to guarantee reliable performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.