Description

2-Oxa-8-Azaspiro[4.5]Decan-1-One Hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its unique spirocyclic structure, which is essential for constructing complex molecules with specific biological or material properties. This intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Material Science Research: Employed in the synthesis of specialty polymers, ligands for catalysis, and other functional organic materials.
• Academic & Industrial R&D: Serves as a versatile scaffold for medicinal chemistry, combinatorial chemistry, and process development studies.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.

Basic Information

Product Name	2-Oxa-8-Azaspiro[4.5]Decan-1-One Hydrochloride
CAS No.	4427-25-2
Molecular Formula	C8H14ClNO2
Molecular Weight	191.66 g/mol
Synonyms	1-Oxa-8-Azaspiro[4.5]decan-2-one hydrochloride; 8-Aza-1-oxaspiro[4.5]decan-2-one hydrochloride; 2-Oxa-8-azaspiro[4.5]decan-1-one HCl; Spirocyclic lactam hydrochloride; Tetrahydro-2H-pyran-4,2'-[1,3]oxazinan]-6'(3'H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Oxa-8-Azaspiro[4.5]Decan-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.