Description

4-Pyridinecarboxamide,n-Hydroxy-(9Ci) is a versatile pyridine derivative and a key hydroxamic acid building block. This compound matters for its role as a critical intermediate in the synthesis of more complex molecules, particularly those with metal-chelating or enzyme-inhibiting properties. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of histone deacetylase (HDAC) inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel fungicides and herbicides that require hydroxamic acid functional groups.
• Metal Chelation & Catalysis: Acts as a ligand for metal ions in catalytic systems and for the extraction or sensing of specific metals.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and proteomics research due to its hydroxamate moiety.
• Material Science: Utilized in the creation of functional polymers and coatings with specialized surface properties.
• Organic Synthesis Building Block: A versatile synthon for constructing heterocyclic compounds and complex molecular architectures.

Basic Information

Product Name	4-Pyridinecarboxamide,n-Hydroxy-(9Ci)
CAS No.	4427-22-9
Molecular Formula	C6H6N2O2
Molecular Weight	138.12 g/mol
Synonyms	N-Hydroxyisonicotinamide; N-Hydroxy-4-pyridinecarboxamide; Isonicotinic acid hydroxamide; 4-Pyridinehydroxamic acid; Pyridine-4-hydroxamic acid; N-Hydroxypyridine-4-carboxamide; 4-Carbamoylpyridine N-oxide (tautomer); Picolinohydroxamic acid (isomer)
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxamide,n-Hydroxy-(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.