Description

1-Isocyanato-4-Methanesulfonylbenzene is a specialized aromatic isocyanate derivative, distinguished by the presence of a methanesulfonyl (mesyl) functional group. This unique bifunctional structure makes it a valuable high-performance building block for synthesizing advanced polymers and fine chemicals. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries to develop novel compounds with tailored properties.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of sulfonamide-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Polymer Modification: Serves as a reactive monomer for producing polyurethanes, polyureas, and other polymers with improved thermal stability and chemical resistance.
• Cross-linking Agent: Imparts covalent cross-links in coatings, adhesives, and elastomers to enhance durability and performance.
• Material Science Research: Employed in developing advanced materials like liquid crystals, dendrimers, and functional surfaces.
• Chemical Probe Development: Useful in bioconjugation and labeling strategies for biochemical and diagnostic applications.

Basic Information

Product Name	1-Isocyanato-4-Methanesulfonylbenzene
CAS No.	4418-85-3
Molecular Formula	C8H7NO3S
Molecular Weight	197.21 g/mol
Synonyms	4-Isocyanatophenyl methyl sulfone; p-Isocyanatophenyl methyl sulphone; 4-Methanesulfonylphenyl isocyanate; Methylsulfonylphenyl isocyanate; 1-Isocyanato-4-(methylsulfonyl)benzene; NSC 163081; 4-(Methylsulfonyl)phenyl isocyanate
EINECS	Contact for details

Quality Control

Our production of 1-Isocyanato-4-Methanesulfonylbenzene adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.