Description

17-Ethynyl-18-Methylestra-5(10),9(11)-Dien-17-Ol-3-One is a high-purity synthetic steroid intermediate with a complex, modified estrane structure. This compound is valued for its role as a critical building block in the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and oncology. It is primarily sought by advanced pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial research for studying structure-activity relationships (SAR) of steroid hormones.
• Hormone Analog Development: Serves as a starting material for creating modified estrogens and other hormonal analogs with targeted biological activity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing complex, high-value specialty chemicals.
• Reference Standard: Can be utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	17-Ethynyl-18-Methylestra-5(10),9(11)-Dien-17-Ol-3-One
CAS No.	4412-59-3
Molecular Formula	C22H28O2
Molecular Weight	324.46 g/mol
Synonyms	17α-Ethynyl-18-methylestra-5(10),9(11)-dien-17β-ol-3-one; 18-Methyl-17α-ethynylestra-5(10),9(11)-diene-3,17β-diol-3-one; 17-Ethynyl-18-methyl-5(10),9(11)-estradien-17-ol-3-one; NSC 121698; 17β-Hydroxy-17α-ethynyl-18-methylestra-5(10),9(11)-dien-3-one
EINECS	Contact for details

Quality Control

Our 17-Ethynyl-18-Methylestra-5(10),9(11)-Dien-17-Ol-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.