Description

2-(Trichloromethyl)Pyridine is a halogenated pyridine derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a reactive trichloromethyl group on the pyridine ring, makes it a valuable building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyridine moiety is a common pharmacophore.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the creation of functionalized polymers, liquid crystals, or organic electronic materials due to its modifiable aromatic system.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A crucial raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Trichloromethyl)Pyridine
CAS No.	4377-37-1
Molecular Formula	C6H4Cl3N
Molecular Weight	196.46 g/mol
Synonyms	2-(Trichloromethyl)pyridine; α,α,α-Trichloro-2-picoline; 2-Pyridyltrichloromethane; 2-Trichloromethylpyridine; (Trichloromethyl)pyridine; Pyridine, 2-(trichloromethyl)-; 2-TCP
EINECS	224-490-8

Quality Control

Our 2-(Trichloromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for purity, appearance, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.