Description

2,6-Dimethyl-4-Phenyl-Nicotinic Acid Ethyl Ester CAS NO 4350-44-1 is a high-value, substituted nicotinate ester that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Building block for developing advanced pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymeric materials due to its aromatic and ester functionalities.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	2,6-Dimethyl-4-Phenyl-Nicotinic Acid Ethyl Ester
CAS No.	4350-44-1
Molecular Formula	C16H17NO2
Molecular Weight	255.31 g/mol
Synonyms	Ethyl 2,6-Dimethyl-4-phenylnicotinate; 4-Phenyl-2,6-dimethylnicotinic Acid Ethyl Ester; 2,6-Dimethyl-4-phenyl-3-pyridinecarboxylic Acid Ethyl Ester; Ethyl 4-Phenyl-2,6-lutidinate; 3-Carbethoxy-2,6-dimethyl-4-phenylpyridine; 4350-44-1; Ethyl 2,6-dimethyl-4-phenyl-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-4-Phenyl-Nicotinic Acid Ethyl Ester is produced under strict quality management protocols. We ensure batch-to-batch consistency and high purity through rigorous analytical testing, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.